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Brian K. Jefferson, MD

CURRICULUM VITAE

Education

Vanderbilt University School of Medicine

MD, May 1998
The Rudolph H. Kampmeier Prize in Clinical Medicine, 1998
Alpha Omega Alpha, 1997

University of Missouri-Columbia

BS Honors Ag; May 1993
Major - Biochemistry


Professional Experience

  • Cleveland Clinic Foundation Department of Cardiology
Interventional Cardiology Fellow
  • Cleveland Clinic Foundation Department of Cardiology
Cardiovascular Fellow, 2001-2005
  • Johns Hopkins Hospital Department of Internal Medicine
Assistant Chief of Service,
Osler Medical Service, 2002 – 2003
  • Johns Hopkins Hospital Department of Internal Medicine
Internal Medicine Residency, 1999 – 2001
  • Johns Hopkins Hospital Department of Internal Medicine
Internship, 1998 – 1999

Licensure

  • State of Maryland: No. D58581. Exp 09/30/2004
  • State of Ohio: No. 57.005267. Exp 10/01/2008

Certification

  • American Board of Internal Medicine
Certification in Internal Medicine 2001
Certification in Cardiovascular Medicine 2005
Certification in Interventional Cardiology 2006

Publications

  1. Luo AK, Jefferson BK, Garcia MJ, Ginsburg GS, Topol EJ. Challenges in The Phenotypic Characterization of Patients in Genetic Studies of Coronary Artery Disease. A Proposal for Uniform Standards. (Accepted for publication, J Med Gen)
  2. Bavry AA, Chiu JH, Jefferson BK, Nissen SE, Smedira NG, Bhatt DL, Ellis SG, Whitlow PL. Late Coronary Aneurysm after Drug Eluting Stent Implantation. (Accepted for publication, Am J Med)
  3. Jefferson BK, Kottke-Marchant K, Murugesan G, Gerber CE, Kaldus T, Cannata R, Goormastic M, Topol EJ. Prevalence of Aspirin Resistance in Patients with a History of Myocardial nfarction. (Submitted)
  4. Jefferson, BK, Topol EJ. Molecular Mechanisms of Myocardial Infarction. Curr Probl Cardiol. 2005 Jul;30(7):333-74.
  5. Bavry A, Jefferson BK. Access to Catheterisation Facilities in Patients Admitted With Acute Coronary Syndromes. BMJ, rapid responses, 19 February 2005.
  6. Jefferson, BK, Chiu JH, Tuzcu EM, Lincoff AM. Bivalirudin Use in Primary Percutaneous Coronary Intervention in a Patient at High Risk for Thromboembolic Complications. Journal of Invasive Cardiology. Dec 2004; 6(9)
  7. Jefferson BK, Foster J, McCarthy JJ, Ginsburg, G, Parker A, Kottke-Marchant K, Topol EJ. Aspirin Resistance and a Single Gene, Am J Cardiol. 2005 Mar 15;95(6):805-8.
  8. Jefferson BK, Hazen S, Topol EJ. Lp-PLA2: a new marker of vascular risk. Med Lett Drugs Ther. 2003 Oct 13;45(1167):83.
  9. Piccini J, Haldar S, Jefferson BK. Cases from the Osler Medical Service at Johns Hopkins University: Zieve’s syndrome.Am J Med. 2003 Dec 15;115(9):729-31.
  10. Habas AB, Kim Y, Jefferson BK. Cases from the Osler Medical Service at Johns Hopkins University: Pernicious Anemia. Am J Med. 2003 Dec 1;115(8):664-6.
  11. Wanner T, Jefferson BK. Cases from the Osler Medical Service at Johns Hopkins University: Mycosis Fungoides. Am J Med. 2003 Nov;115(7):576-7.
  12. Schiffer JT, Jefferson BK. Cases from the Osler Medical Service at Johns Hopkins University: Unilateral Breast Enlargement as a Complication of a thrombosed AV Fistula. Am J Med. 2003 Oct 1;115(5):04-6.
  13. Reed A, Jefferson BK. Cases from the Osler Medical Service at Johns Hopkins University. Group G Streptococcal Endocarditis. Am J Med. 2003 Sep;115(4):326-8.
  14. Tiong IY, Novaro GM, Jefferson BK, Monson M, Smedira N, Penn MS. Bacterial endocarditis and functional mitral stenosis: a report of two cases and brief literature review. Chest. 2002 Dec;122(6):2259-62.
  15. Schiffer JT, Park C, Jefferson BK. Cases from the Osler Medical Service at Johns Hopkins University: Sister Mary Joseph Nodule. Am J Med. 2003 Jan;114(1):68-70.
  16. Jefferson, BK. Cal Ripken, Jr., and Prinivil. New England Journal of Medicine. 1998 Dec 31; 339(27): 2024-5.
  17. Jefferson, BK. Should Stars Pitch Prescription Drugs? The New York Times. Jan 12, 1999: D8.

Chapters

  1. Jefferson BK, Topol EJ. Platelet Genomics, in Platelets in Cardiovascular disease. Deepak Bhatt ed. (In Press)
  2. Jefferson BK, Providencia. In The ABX Guide: Diagnosis & Treatment of Infectious Diseases (Abx Guide). John Bartlett, Paul Auwaerter, Paul Pham, ed. 2005
  3. Jefferson, BK, Topol ET. Genetics and Cardiovascular Disease in The Cleveland Clinic Cardiovascular Medicine Board Review. Brian Griffin, Curtis Rimmerman ed.

Clinical Trial Experience

  1. SHINE: A randomized dose-Ranging Study of Hexadecasaccharide including Active including Active Control in patients with Unstable Angina or NSTEMI Scheduled to Undergo PCI, Adjudication committee. 2006-present.
  2. ACTIVATE: ACAT inhibition on the progression of coronary atherosclerosis, Adjudication committee. 2004-2005
  3. CAPTIVATE: Efficacy and Safety of the ACAT Inhibitor C-505 (Pactimibe) for Reducing the Progression of Carotid Artery Disease, Adjudication committee. 2005-2006

Abstracts

  1. A VIDEO SHARING WEB SITE AS A NEW TOOL FOR MEDICAL EDUCATION. V. Dimov, K. Civello, B. Jefferson, K. Uzunova-Dimova, A. Kumar. 2007 International Association of Medical Science Educators – IAMSE. (Submitted)
  2. A Wiki-based Web Site as an Educational Tool for Cardiology Fellows. Ken Civello, Ves Dimov, K Uzunova-Dimova, Brian K. Jefferson, Wassim Fares. 2007 Medical Education for the 21st Century at the Case Western Reserve University School of Medicine Annual Education Retreat
  3. Safety and Efficacy of IVUS-guided Lumen Re-entry Devices for the Percutaneous Revascularization of Chronic Total Occlusions of the Superficial Femoral Artery. Eduardo Infante de Oliveira, Vivek Rajagopal, Matthews Chacko, Chrisital Simpfendorfer, Brian K Jefferson, Christopher Bajzer, Deepak Bhatt, Samir Kapadia. 2007 American College of Cardiology Scientific Sessions
  4. Safety and efficacy of carotid artery stenting in patients with a history of neck irradiation. Brian K. Jefferson, Vivek Rajagopal, Samir R. Kapadia, Hitinder S. Gurm, Alex Abou-Chebl, Mikhael Mazighi, Matthews Chacko, Christian Simpfendorfer, Edurado Infante de Oliveira, Deepak L. Bhatt, Chris Bajzer, Jay S. Yadav. 2007 American College of Cardiology Scientific Sessions
  5. Age >80 is an independent risk factor for adverse outcomes after carotid stenting Vivek Rajagopal, Samir R. Kapadia, Hitinder S. Gurm, Deepak L. Bhatt, Surabhi Madhwal, Alex Abou-Chebl, Mikhael Mazighi, Juhana Karha, Matthews Chacko, Brian K. Jefferson, Christian Simpfendorfer, Chris Bajzer, Jay S. Yadav 2007 American College of Cardiology Scientific Sessions
  6. Favorable outcomes for carotid stenting in patients with restenosis after carotid endarterectomy Brian K. Jefferson, Vivek Rajagopal, Samir R. Kapadia, Hitinder S. Gurm, Deepak L. Bhatt, Matthews Chacko, Christian Simpfendorfer, Christopher Bajzer, Alex Abou-Chebl, Jay S. Yadav. Moderated Poster. 2007 American Heart Association Scientific Sessions
  7. A Normal Intracranial Angiogram Predicts a Favorable Outcome in Patients with Neurologic Deficits during Carotid Artery Stenting Vivek Rajagopal, Mikhael Mazighi, Samir R. Kapadia, Hitinder S. Gurm, Deepak L. Bhatt, Juhana Karha, Patricia Gum, Brian K. Jefferson, Matthews Chacko, Christian Simpfendorfer, Christopher Bajzer, Alex Abou-Chebl, Jay S. Yadav. 2007 American Heart Association Scientific Sessions.
  8. Favorable Outcomes of Women Undergoing Carotid Stenting. Vivek Rajagopal, Hitinder Gurm, Alex Abou-Chebl, Samir Kapadia, Deepak Bhatt, Mathews Chacko, Brian Jefferson, Christian Simpfendorfer, Chris Bajzer, Jay S. Yadav. 2006 American College of Cardiology Scientific Sessions
  9. Aspirin Resistance Is Associated With A Single Nucleotide Polymorphism in the P2Y1 ADP Receptor gene. Brian K. Jefferson, MD, Jennifer H. Foster MPH, Jeanette J. McCarthy PhD, Kandice Kottke-Marchant MD, PhD, Eric J. Topol MD. Oral presentation 2004 American College of Cardiology Scientific Sessions

Invited Lectures

  • The Diagnosis and Management of Antiplatelet Resistance
Faculty
Satellite Symposium 2004 AHA
November 2004
  • The Philip A. Tumulty Lectures
vWF processing and ADAMTS activity in TTP
Topics In Clinical Medicine At Johns Hopkins
May 2003
  • Cleveland Clinic Atherothrombosis Society
vWF: Beyond Bleeding
January 2002

Web Projects

  1. Jefferson, BK, http://www.askdrwiki.com. Co-founder. Current
  2. Jefferson, BK, http://medhelp.org. Consultant and administrator of Cardiovascular patient forums. Current.
  3. Jefferson, BK, Providencia. http://www.hopkins-abxguide.org/, 2003
  4. Jefferson, BK. Lactobacillus. http://www.hopkins-abxguide.org/, 2003
  5. Jefferson, BK The Diagnosis & Management of Antiplatelet Resistance http://www.theheart.org/viewArticle.do?primaryKey=329747, 2003
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